Description
This newsletter explains the PREVENT (Predicting Risk of cardiovascular disease EVENTs) equations introduced in the 2026 CKM Guideline. PREVENT provides 10‑ and 30‑year risk estimates for atherosclerotic cardiovascular disease, heart failure, and total cardiovascular disease, incorporating kidney (eGFR, UACR) and metabolic (HbA1c) variables alongside traditional risk factors. The item outlines the two clinical thresholds (10‑year risk ≥20% defining CKM Stage 3; ≥7.5% informing pharmacotherapy prioritisation), describes how to combine predicted risk with expected treatment benefit, and highlights PREVENT’s use in trial design and clinical decision-making to better stratify patients and justify therapy escalation.